Pores enlarge and texture roughens when dermal collagen thins and stops supporting the pore walls. Trifill PRO opens the space under the dermis with pressurized CO₂ gas and injects Olidia myo (PLLA) evenly into it so collagen rebuilds. Red and brown marks left by acne fade as blood flow recovers and the dermis regenerates, and pitted scars and stretch marks are treated the same way with the adhesion released as well. Gas, solution and gas, all in one shot.
Trifill PRO is a CO₂ subcision and drug delivery system developed by MCURE. Instead of scraping adhesions with a needle as in manual subcision, it releases the tissue under the skin with pressurized CO₂ gas and, within the same shot, injects a regenerative solution precisely into the released space and spreads it evenly with a second burst of gas. At Dr. NewCell that solution is Olidia myo, a PLLA collagen stimulator, which restores dermal density: across the whole dermis for enlarged pores and rough texture, and into the released floor for pitted scars.
Pores, texture and acne marks are the most common Trifill PRO consultations at Dr. NewCell, followed by pitted scars and stretch marks. In every case the cause is in the dermis.
Pores and scars share one cause: the dermis
Pores enlarge and texture roughens when dermal collagen density falls and no longer supports the pore walls; pitted scars and stretch marks add a fibrous band that holds the surface down. Treatments that heat from above refine the surface but leave dermal density and that band untouched. Trifill PRO works from below.
When dermal collagen breaks and adheres, the surface sinks. Concept illustration.
CO₂ enters beneath the dermis and opens a space; where there is a scar it also detaches the fibrous band. Wider and more even than needle subcision by hand.
Before the space closes, Olidia myo goes precisely into that layer. Less risk of lumps (nodules) from product landing in the wrong layer.
A second burst of gas disperses the solution across the dermis around the pores. New collagen then supports the pore walls and fills the scar floor.
Evidence
The manufacturer injected dye into porcine skin to compare methods. With the same volume, injection after CO₂ subcision spreads wide and even, while hand subcision or a plain injection pools at one point. For a treatment that must reach the dermis around every pore and the whole scar floor evenly, this difference decides the result.
| Study | Subjects · method | Findings |
|---|---|---|
| Chin et al., Ann Plast Surg 2013 | 34 patients with facial wrinkles, intradermal CO₂ followed by sequential HA, 3–11 month follow-up | Dermis 1.6× thicker 12 months after CO₂ alone (2.64 vs 1.62 mm). CO₂ + HA dermis 1.9× thicker than HA alone (4.21 vs 2.19 mm). 91% highly satisfied |
| Koutná, Aesthetic Medicine 2011 | Carboxytherapy protocols by indication | Atrophic scars: 2–6 sessions 3–4 weeks apart, "very good". Deep scars need the fibrous strands under the scar destroyed. Stretch marks 2–4 weeks apart, "good" |
| Zelenková, Glob Dermatol 2017 | Mechanism and clinical experience | CO₂ lowers tissue pH, increasing oxygen release (Bohr effect) and blood flow. Pain is momentary; bruising in 5% if a vessel is hit. Change usually within 7–14 days after two sessions |
The literature supports CO₂ gas injection itself and the sequential injection of a regenerative substance after CO₂. Trifill PRO is the device that performs that sequence automatically in one shot.
Different concerns, different tools
Enlarged pores and rough texture call for PLLA spread widely through the whole dermis. Pitted acne scars are classified by shape as ice pick, boxcar or rolling, and each responds differently. Trifill PRO suits pores and texture, and rolling and boxcar scars where adhesion is the cause, best; narrow ice pick scars are combined with other treatments.
| Concern | Shape · cause | Fit for Trifill PRO |
|---|---|---|
| Enlarged pores · rough texture | Pore walls sag as dermal collagen density falls | Best fit · three-step dispersion across the whole dermis |
| Red · brown acne marks | Dilated vessels and pigment left after inflammation | Good fit · blood-flow recovery + dermal regeneration; dark pigment combined with a laser |
| Rolling scars | Wide, gently sunken; a fibrous band underneath | Best fit · releasing the adhesion is the key |
| Boxcar | Wide depression with sharp edges; dermal loss | Good fit · release, then fill the floor with PLLA |
| Ice pick | Narrow, deep pits | Combine rather than alone · surface with Potenza or TCA |
| Stretch marks | Torn dermal collagen, white atrophic lines | Good fit · more sessions needed |
| Static neck · forehead lines | Deeply folded grooves with adhesion | Good fit · grooves Botox cannot smooth |
Laser · microneedle RF · subcision · Trifill PRO
Dr. NewCell runs Potenza (microneedle RF) and Trifill PRO together. Potenza provides heat stimulation at the surface; Trifill PRO rebuilds dermal collagen density and releases adhesion. For pores and texture, using the two in order lasts longest.
| Fractional laserFraxel etc. | Microneedle RFPotenza etc. | Manual subcisionneedle · cannula | Trifill PROCO₂ subcision + PLLA | |
|---|---|---|---|---|
| Principle | Micro-injury with heat, regeneration | RF at needle tips coagulates the dermis | Needle cuts the fibrous band | CO₂ gas releases adhesion + regenerative injection |
| Releases adhesion | No | No | Yes (depends on hand feel) | Yes (gas pressure, wide and even) |
| Regenerative injection | Separate treatment | Drug delivery possible | Separate injection | PLLA injected and spread in the same shot |
| Best suited concerns | Surface texture, shallow scars | Pore openings, texture, shallow scars | Rolling | Pores · texture (dermal density), rolling · boxcar, stretch marks, static lines |
| Pain · anesthesia | Numbing cream, strong heat | Numbing cream | Local anesthetic injection | Numbing cream, brief pressure |
| Downtime | Crusts · redness 5–7 days, pigmentation risk | Redness 2–3 days | Bruising · swelling 1–2 weeks | Injection marks · redness 1–2 days |
| Sessions | 3–5 | 3–5 | 1–3 | 2–3, 4 weeks apart |
| At Dr. NewCell | Ask in consultation | Potenza combination programs | — | Trifill PRO + Olidia myo |
Treatment characteristics are based on general operating principles and manufacturer data; results and downtime vary with the scar and the treatment plan. Which treatment suits you is decided after the doctor examines the scar type in consultation.
Release is immediate, filling takes time
The release of adhesion shows at once; the collagen PLLA builds fills in over weeks. That is why the second session is scheduled four weeks later.
Gas and solution fill the space under the dermis so the skin around the pores feels firmer, and scars become shallower as the adhesion detaches. Injection marks, redness and slight swelling are present.
Redness and swelling subside. Washing and makeup are fine from the next day.
New collagen forms around the PLLA; pores begin to look tighter and texture smoother. The second session is done at four weeks.
Collagen production continues after the course, pores and texture hold, scar depth softens, and the PLLA gradually breaks down and leaves nothing behind.
After release and fill
Olidia myo clinical cases. Scar cases were photographed after two sessions four weeks apart.
Results vary with scar depth, adhesion and lifestyle; these cases do not appear identically in every patient. Photos: Olidia myo manufacturer (K.P BIO) clinical cases, published with patient consent.
Dermis with Trifill PRO, surface with Potenza
Neither pores and texture nor scars finish with one treatment. We rebuild dermal density and lift depth first, then deal with surface texture, pore openings and red marks in order.
Trifill PRO rebuilds dermal collagen density first; four weeks later Potenza refines pore openings and surface texture. In the reverse order the surface improves briefly and then reverts. If pitted scars are present, the adhesion is released in the same sequence.
Trifill PRO lightens the marks through blood-flow recovery and dermal regeneration; remaining redness and texture are finished with Rejuran or skin boosters. Dark brown marks get a pigment laser as well. Can be done the same day, Trifill PRO first.
Lines made by movement get Botox; grooves that stay folded at rest are released and filled with Trifill PRO. The same area is spaced two weeks apart.
If the scarred cheek has started to sag, Trifill PRO fixes the depth first, then Alltite lifts firmness and the line across the whole dermis. See Alltite lifting
Process
Which layer to fill, how much, and where to release decide the result. Misreading pores, texture or scar type means no effect or over-filling, so the doctor handles everything from consultation to treatment.
Seated, the doctor checks pore laxity and texture, then presses each scar to tell rolling, boxcar, ice pick and stretch marks apart and marks where adhesion is the cause.
Topical anesthetic, then cleansing. No injected or sedation anesthesia.
The handpiece is placed vertically on the skin; suction holds it and gas, solution and gas go in automatically. Pores and texture: the whole cheek in one pass with 20% overlap; scars: one shot each.
You see the shallower pits in the mirror together, then decide on the second session in four weeks and any combination such as Potenza.
Aftercare
FAQ
Visiting from abroad
Trifill PRO tightens enlarged pores and smooths rough texture by filling the dermis with PLLA (Olidia myo) after opening it with CO₂ gas, and repairs pitted acne scars and stretch marks by releasing the adhesion underneath. Two or three sessions four weeks apart are ideal. If you can visit only once, we do the first session in Seoul and follow your progress by LINE, KakaoTalk or email.
7F Namyoung Building, 458 Gangnam-daero, Gangnam-gu, Seoul — Dr. NewCell Clinic Gangnam Main Branch
Line 9: from Sinnonhyeon Station exit 5, walk straight; 7F of the building right next to the Apple Store
Shinbundang Line: Sinnonhyeon Station exit 6, to your left; 7F of the building between Starbucks and the Apple Store
Gangnam Station exit 11, about 8 minutes on foot
*Free parking for patients
Director Dr. Shin Yong-bae · 16 years in anti-aging · 9 doctors
Trifill PRO consultations are done by the doctor. If you booked at an event price, that price stands.
The information on this page does not replace a consultation with a doctor. Results and side effects vary between individuals; redness, swelling, bruising and warmth may occur. Before-and-after photos are published with patient consent and are unretouched. Device and literature information is based on manufacturer data and the cited papers. Dr. NewCell Clinic · Business registration 380-22-01983.
